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Home - Products - Others - Other Targets - N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide

CAS No. 1383373-65-6

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide( —— )

Catalog No. M35310 CAS No. 1383373-65-6

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide
  • Note
    Research use only, not for human use.
  • Brief Description
    N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.
  • Description
    TAU-IN-1 (compound 051) is a TAU protein inhibitor with an EC50 value of 325 nM. TAU-IN-1 can be used in the study of neurodegenerative diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Microtubule Associated
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1383373-65-6
  • Formula Weight
    399.87
  • Molecular Formula
    C24H18ClN3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(CNC(=O)C1=C(C=CC=C1)C2=CC=C(C#N)C=C2)C=3C=4C(NC3)=CC=C(Cl)C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gerard Griffioen et al. Novel compounds for the treatment of neurodegenerative diseases. WO2012080220A1.2012-06-21.
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